Methyl N-Cbz-3-piperidinecarboxylate - Names and Identifiers
Name | piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester
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Synonyms | Methyl N-Cbz-3-piperidinecarboxylate Methyl 1-Cbz-piperidine-3-carboxylate 1-benzyl 3-Methyl piperidine-1,3-dicarboxylate N-Cbz-3-piperidine-carboxylic acid methyl ester N-benzyloxycarbonyl nipecotic acid methyl ester O1-benzyl O3-methyl piperidine-1,3-dicarboxylate PIPERIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER 3-METHYL PIPERIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER 3-METHYL ESTER piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester
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CAS | 174543-74-9
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InChI | InChI=1/C15H19NO4/c1-19-14(17)13-8-5-9-16(10-13)15(18)20-11-12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3 |
Methyl N-Cbz-3-piperidinecarboxylate - Physico-chemical Properties
Molecular Formula | C15H19NO4
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Molar Mass | 277.32 |
Density | 1.187±0.06 g/cm3(Predicted) |
Boling Point | 390.4±42.0 °C(Predicted) |
pKa | -2.53±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.538 |
Methyl N-Cbz-3-piperidinecarboxylate - Introduction
piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester, also known as N-butoxycarbonyl-3-piperidinecarboxylic acid methyl ester, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
piperidine-1,3-dicarboxylic acid 1-benzoyl ester 3-methyl ester is a colorless to light yellow liquid with a specific aroma. It is stable at room temperature, but susceptible to light and oxidation and decomposition. It is soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane.
Use:
piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester is an important intermediate in the field of organic synthesis. It can be used as a synthetic raw material for drugs, pesticides and functional materials. In addition, it is also used for the removal of protecting groups and extraction separation in organic synthesis reactions.
Method:
piperidine-1, the preparation of 3-dicarboxylic acid 1-benzyl ester 3-methyl ester usually adopts the method of chemical synthesis. A common preparation method is to react pidoxine with formyl chloride, and then react with ammonia and butanol to form piperidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester.
Safety Information:
piperidine-1,3-dicarboxylic acid 1-benzoyl ester 3-methyl ester is a chemical that requires safety attention when used. It may cause irritation to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment such as safety glasses, gloves and protective face masks when using it. At the same time, it should be operated in a well-ventilated place to avoid inhalation and contact. During storage, it should be placed in a cool, dry place, away from fire and oxidizing agents. If it is accidentally touched or ingested, seek medical attention immediately and provide the appropriate safety data sheet or label.
Last Update:2024-04-09 21:11:58